1. US Highway 441 runs for 939 miles, spanning from Florida to Tennessee.
2. The highway connects many major urban areas including Miami, Orlando, Ocala, Gainesville, Athens, and Knoxville.
3. US Highway 441 passes through the Great Smoky Mountains National Park, a UNESCO World Heritage Site that straddles the ridge of the Great Smoky Mountains, part of the Blue Ridge Mountains, themselves part of the Appalachian Trail.
4. Route 441 is mentioned in the famous rock song “American Girl,” by Tom Petty and the Heartbreakers. As the song’s lyrics go, “She could hear the cars roll by/Out on 441/Like waves crashin’ on the beach.”
5. There are currently 12 bannered routes that are part of US Highway 441, including alternate routes, truck stops, business loops, and bypass routes.
6. Florida had different colors for different highways until the 1990s, when the typical black and white highway signs became federally mandated. Between 1956 and 1993, Route 441 was marked in Florida by a brown “shield.”
7. The stretch of US 441 in Florida from SR 331 to the line between Alchua County and Marion County is notable for providing access to Florida’s natural beauty, including Paynes Prairie State Preserve and the Lake Wauberg recreational area near the University of Florida.
8. US 441 takes drivers through Madison, Georgia, a unique town east of Atlanta. Madison was one of the only towns that was not burned down during the Civil War, and it is home to over 100 preserved antebellum homes.
9. Multiple college campuses can be accessed via Route 441, including Gainesville’s University of Florida and the University of Georgia in Athens.
10. US 441 was first used in 1926 as an 87 mile-long highway connecting Ocala and Orlando.
11. Since 1952, Route 441’s north terminus has been Lake City, TN and its south terminus has been Miami, FL.
12. US 441 was first initiated as part of the 1925 plan of the federal Bureau of Public Roads.
13. Route 441 will take drivers to the ballpark belonging to the minor league baseball team the Tennessee Smokies.
14. Use US Highway 441 to access Dolly Parton’s home, Dollywood, in Pigeon Forge, TN.
15. The famous Florida Keys can be reached via 441.
16. With a detour of a few miles, drivers on Route 441 can see the view from Clingmans Dome, the highest point in the state of Tennessee.
17. The Black Rock Mountain State Park in Georgia is another worthy attraction along Route 441.
18. One of Georgia’s “seven natural wonders,” the Tallulah Gorge, can be accessed by Route 441. It is often called the “Grand Canyon of the South.”
19. A frequent favorite roadside attraction is “Goats on a Roof,” a store and restaurant in Northern Georgia where visitors can watch goats atop the building roof.
20. US 441 was part of the GRIP (Governor’s Road Improvement Program) in Georgia to spur economic development and improve the highway’s infrastructure.
21. The stretch of Highway 441 in the Great Smoky Mountains prohibits trucks and other commercial vehicles.
22. US 441 works its way through the town of Cherokee, NC, which is located within an Indian reservation.
23. US Highway 441 connects with US 41 in Miami and US 25W in Lake City, TN.
24. Route 441 garners a mention in country singer Brantley Gilbert’s song “Best of Me.”
25. US Route 441 is considered one of the most scenic stretches of highway in the entire country, and a particularly beautiful way to drive through the South.
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